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Review
. 2006 Mar 13;172(6):803-8.
doi: 10.1083/jcb.200512082. Epub 2006 Mar 6.

RNA granules

Paul Anderson  1 , Nancy Kedersha
Affiliations
Review

RNA granules

Paul Anderson et al. J Cell Biol. .

Abstract

Cytoplasmic RNA granules in germ cells (polar and germinal granules), somatic cells (stress granules and processing bodies), and neurons (neuronal granules) have emerged as important players in the posttranscriptional regulation of gene expression. RNA granules contain various ribosomal subunits, translation factors, decay enzymes, helicases, scaffold proteins, and RNA-binding proteins, and they control the localization, stability, and translation of their RNA cargo. We review the relationship between different classes of these granules and discuss how spatial organization regulates messenger RNA translation/decay.

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Figures

Figure 1.
Figure 1.
Comparative composition of cytoplasmic RNA granules. Green, present; red, absent. *, weakly present.
See this image and copyright information in PMC

References

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