Finding the molecular basis of complex genetic variation in humans and mice
- PMID: 16524828
- PMCID: PMC1609339
- DOI: 10.1098/rstb.2005.1798
Finding the molecular basis of complex genetic variation in humans and mice
Abstract
I survey the state of the art in complex trait analysis, including the use of new experimental and computational technologies and resources becoming available, and the challenges facing us. I also discuss how the prospects of rodent model systems compare with association mapping in humans.
References
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- Alemayehu A, Breen L, Krenova D, Printz M.P. Reciprocal rat chromosome 2 congenic strains reveal contrasting blood pressure and heart rate QTL. Physiol. Genomics. 2002;10:199–210. - PubMed
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