Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Jul;32(3):464-73.
doi: 10.1093/schbul/sbj064. Epub 2006 Mar 8.

Ten-year recovery outcomes for clients with co-occurring schizophrenia and substance use disorders

Affiliations

Ten-year recovery outcomes for clients with co-occurring schizophrenia and substance use disorders

Robert E Drake et al. Schizophr Bull. 2006 Jul.

Abstract

The long-term courses of people with schizophrenia and of those with substance use disorder have been studied separately and extensively. The long-term course of clients with co-occurring schizophrenic and substance use disorders has, however, not been examined. This article reports 10-year outcomes for 130 clients with co-occurring schizophrenic and substance use disorders in the New Hampshire Dual Diagnosis Study. In addition, we report on 6 "recovery outcomes," identified by dual diagnosis clients, as examples of positive coping behaviors. Longitudinal data were modeled using generalized estimating equation (GEE) methods. Participants improved steadily over 10 years in the outcome domains of symptoms, substance abuse, institutionalization, functional status, and quality of life. Further, at the 10-year follow-up, substantial proportions were above cutoffs selected by dual diagnosis clients as indicators of recovery: 62.7% were controlling symptoms of schizophrenia; 62.5% were actively attaining remissions from substance abuse; 56.8% were in independent living situations; 41.4% were competitively employed; 48.9% had regular social contacts with non-substance abusers; and 58.3% expressed overall life satisfaction. These 6 outcomes were only weakly interrelated over time, suggesting that recovery, as defined by clients, is a multidimensional concept. Overall, the 10-year findings on recovery outcomes provide a hopeful long-term perspective for dual diagnosis clients.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Patterns of 6 Indicators of Recovery Over Time (N = 130).
Fig. 2
Fig. 2
Proportion of Composite Recovery Scores at Baseline, 3 Years, and 10 Years for Schizophrenia and Schizoaffective Patients With Co-Occurring Substance Use Disorders (N = 130).

References

    1. Regier DA, Farmer ME, Rae DS, Locke BZ, Keith SJ, Judd LL. Comorbidity of mental disorders with alcohol and other drug abuse. JAMA. 1990;264:2511–2518. - PubMed
    1. Drake RE, Osher FC, Noordsy DL, Hurlbut SC, Teague GB, Beaudett MS. Diagnosis of alcohol use disorders in schizophrenia. Schizophr Bull. 1990;16:57–67. - PubMed
    1. Duke PJ, Pantelis C, Barnes RE. South Westminster Schizophrenia Survey: alcohol use and its relationship to symptoms, tardive dyskinesia and illness onset. Br J Psychiatry. 1994;164:630–636. - PubMed
    1. Mueser KT, Yarnold PR, Levinson DF, et al. Prevalence of substance abuse in schizophrenia: demographic and clinical correlates. Schizophr Bull. 1990;16:31–56. - PubMed
    1. Ziedonis D, Trudeau K. Motivation to quit using substances among individuals with schizophrenia: implications for a motivation-based treatment model. Schizophr Bull. 1997;23:229–238. - PubMed

Publication types

MeSH terms