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Comparative Study
. 2006 May;10(2):251-3.
doi: 10.1007/s11030-005-9011-3. Epub 2006 Mar 10.

A one-pot entry to a novel 3-H-benzo[d]pyrazolo[1,5-b]isothiazole ring system

Paola Vicini  1 , Matteo Incerti, Rocco Ferretti, Franca Zanardi
Affiliations
Comparative Study

A one-pot entry to a novel 3-H-benzo[d]pyrazolo[1,5-b]isothiazole ring system

Paola Vicini et al. Mol Divers. 2006 May.

Abstract

The phosphorus ylide obtained from the reaction between 2-aminobenzo[d]isothiazol-3-one and dimethyl acetylenedicarboxylate in the presence of triphenylphosphine undergoes a smooth intramolecular Wittig-type reaction to produce, in a one-pot reaction, 3-H-benzo[d]pyrazolo[1,5-b]isothiazole-2,3a-dicarboxylic acid dimethyl ester, a novel functionalized heterocyclic compound.

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