doi: 10.1093/jnci/54.5.1231.
Immunologic aspects of 1, 2-dimethylhydrazine-induced colon tumors in rats
- PMID: 165314
- DOI: 10.1093/jnci/54.5.1231
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Immunologic aspects of 1, 2-dimethylhydrazine-induced colon tumors in rats
J Natl Cancer Inst.
1975 May.
Abstract
Investigation of immunologic aspects of colon tumors induced in rats by 1,2-dimethylhydrazine demonstrated that: 1) An antigen in an extract of colon tumors was not detected in the normal colon. It was related to antigens in rat fetuses and did not cross-react immunologically with carcinoembryonic antigen. 2) Mucinous adenocarcinomas of the colon were significantly associated spatially with lymphoid follicles.
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