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. 1991 Sep;173(17):5551-3.
doi: 10.1128/jb.173.17.5551-5553.1991.

Gyrase inhibitors increase the content of knotted DNA species of plasmid pBR322 in Escherichia coli

S Ishii  1 , T Murakami, K Shishido
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Gyrase inhibitors increase the content of knotted DNA species of plasmid pBR322 in Escherichia coli

S Ishii et al. J Bacteriol. 1991 Sep.

Abstract

Treatment of Escherichia coli cells harboring pBR322 with the DNA gyrase inhibitors oxolinic acid and coumermycin A1 led to an increase in the content of knotted pBR322 molecules. This phenomenon was attributed to inhibition of gyrase-catalyzed unknotting of the plasmid DNA knotted by transcription.

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References

    1. Anal Biochem. 1983 Jul 1;132(1):6-13 - PubMed
    1. Nucleic Acids Res. 1985 Oct 25;13(20):7207-21 - PubMed
    1. Proc Natl Acad Sci U S A. 1981 May;78(5):2747-51 - PubMed
    1. Cell. 1982 Nov;31(1):43-51 - PubMed
    1. Cell. 1980 May;20(1):245-54 - PubMed

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