Futility studies: spending a little to save a lot

Editorial

Steven R Schwid et al. Neurology. 2006.

. 2006 Mar 14;66(5):626-7.

doi: 10.1212/01.wnl.0000204644.81956.65.

No abstract available

Comment on

A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease.
NINDS NET-PD Investigators. NINDS NET-PD Investigators. Neurology. 2006 Mar 14;66(5):664-71. doi: 10.1212/01.wnl.0000201252.57661.e1. Epub 2006 Feb 15. Neurology. 2006. PMID: 16481597 Clinical Trial.
Optimizing the ongoing search for new treatments for Parkinson disease: using futility designs.
Tilley BC, Palesch YY, Kieburtz K, Ravina B, Huang P, Elm JJ, Shannon K, Wooten GF, Tanner CM, Goetz GC; NET-PD Investigators. Tilley BC, et al. Neurology. 2006 Mar 14;66(5):628-33. doi: 10.1212/01.wnl.0000201251.33253.fb. Neurology. 2006. PMID: 16534099 Review.
A two-stage design for a phase II clinical trial of coenzyme Q10 in ALS.
Levy G, Kaufmann P, Buchsbaum R, Montes J, Barsdorf A, Arbing R, Battista V, Zhou X, Mitsumoto H, Levin B, Thompson JL. Levy G, et al. Neurology. 2006 Mar 14;66(5):660-3. doi: 10.1212/01.wnl.0000201182.60750.66. Neurology. 2006. PMID: 16534103 Clinical Trial.