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. 2005 Aug;18(4):405-11.
doi: 10.1097/01.aco.0000174957.97759.f6.

Xenon: from stranger to guardian

Robert D Sanders  1 , Mervyn Maze
Affiliations

Xenon: from stranger to guardian

Robert D Sanders et al. Curr Opin Anaesthesiol. 2005 Aug.

Abstract

Purpose of review: Xenon anaesthesia has recently been evaluated in large-scale clinical trials that have demonstrated xenon's safe and effective clinical profile. Despite the relatively high cost of xenon anaesthesia, xenon has clear clinical advantages over other current anaesthetics.

Recent findings: Xenon possesses distinct neuroprotective and cardioprotective properties in addition to a favourable pharmacokinetic profile and analgesic effects. In addition, xenon exerts preconditioning effects in the heart and may offer postoperative, as well as intraoperative, cardio and neuroprotection.

Summary: Further clinical trials are required to evaluate the role that xenon can play in the perioperative period.

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