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. 2006 Feb 28;12(8):1281-6.
doi: 10.3748/wjg.v12.i8.1281.

Clinical correlation of gallstone disease in a Chinese population in Taiwan: experience at Cheng Hsin General Hospital

Chi-Ming Liu  1 , Tao-Hsin Tung, Pesus Chou, Victor Tze-Kai Chen, Chung-Te Hsu, Wu-Shyong Chien, Yeu-Tyng Lin, Hsu-Feng Lu, Hui-Chuan Shih, Jorn-Hon Liu
Affiliations

Clinical correlation of gallstone disease in a Chinese population in Taiwan: experience at Cheng Hsin General Hospital

Chi-Ming Liu et al. World J Gastroenterol. .

Abstract

Aim: To explore the prevalence of gallstone disease (GSD) in Taiwan and condition-associated factors related to it.

Methods: We studied a total of 2386 healthy adults (1235 males and 1151 females) voluntarily admitted to Cheng Hsin General Hospital for a paid physical check-up between January 2002 and December 2002. Blood samples and ultrasound sonography results were collected.

Results: The overall prevalence of GSD among this study-population was 5.3%, including 1.7% (n=40) having a single stone, 2.3% (n=55) having multiple stones, and 1.3% (n=31) having cholecystectomy. The prevalence revealed a statistically significant increase with increasing age (P<0.0001). Females exhibited a greater prevalence of multiple stones than did males (3.0% vs 1.7%, P=0.04). Using multiple logistic regression analysis, the following appeared to be significantly related to the prevalence of GSD: older age (40-49 years vs < 40 years, OR=1.63 [95% CI: 0.76-3.48], 50-59 years vs < 40 years, OR=4.93 [95% CI: 2.43-9.99], 60-69 years vs < 40 years, OR=6.82 [95% CI: 3.19-14.60], > or = 70 years vs < 40 years, OR=10.65 [95% CI: 4.78-23.73]), higher BMI (> or = 27 kg/m2 vs < 24 kg/m2, adjusted OR=1.74 [95% CI: 1.04-2.88]), and higher FPG (> or = 126 mg/dL vs < 110 mg/dL, OR=1.71, 95%CI: 1.01-2.96).

Conclusion: Older age (> or = 50 years), obesity (BMI > or = 27 kg/m2), and type 2 diabetes (FPG > or = 126 mg/dL) are associated with the prevalence of GSD.

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Figures

Figure 1
Figure 1
Gender- and age-specific prevalence of all types of gallstone disease among 2386 Chinese subjects.
See this image and copyright information in PMC

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