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. 1991 Jul 22;103(2):235-8.
doi: 10.1016/0378-1119(91)90278-j.

Nucleotide and deduced amino acid sequences of the gene encoding virion protein 16 of herpes simplex virus type 2

A Cress  1 , S J Triezenberg
Affiliations

Nucleotide and deduced amino acid sequences of the gene encoding virion protein 16 of herpes simplex virus type 2

A Cress et al. Gene. .

Abstract

A virion protein (VP16) of herpes simplex virus (HSV) activates transcription of viral immediate-early genes. We have determined the nucleotide sequence of the virion activator gene from HSV-2, which we term VP16-2. Comparison of the deduced amino acid sequences of the HSV-1 and HSV-2 homologs shows that the VP16-2 gene product retains features determined to be important for transcriptional activation by VP16.

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