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. 2006 May 23;66(10):1571-3.
doi: 10.1212/01.wnl.0000206364.19772.39. Epub 2006 Mar 15.

Long-term follow-up of patients with thalamic deep brain stimulation for epilepsy

D M Andrade  1 , D Zumsteg, C Hamani, M Hodaie, S Sarkissian, A M Lozano, R A Wennberg
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Long-term follow-up of patients with thalamic deep brain stimulation for epilepsy

D M Andrade et al. Neurology. .

Abstract

The authors describe long-term follow-up (mean, 5 years) in patients with anterior (AN) (n = 6) or centromedian (n = 2) thalamic deep brain stimulation (DBS) for epilepsy. Five patients (all AN) had > or = 50% seizure reduction, although benefit was delayed in two until years 5 to 6, after changes in antiepileptic drugs. DBS electrode implantation in AN patients was followed by seizure reduction 1 to 3 months before active stimulation, raising the possibility of a beneficial microthalamotomy effect.

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