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Case Reports
. 2007 May;26(5):792-6.
doi: 10.1007/s10067-006-0200-y. Epub 2006 Mar 16.

Polymyositis associated with focal mesangial proliferative glomerulonephritis with depositions of immune complexes

Yasunobu Takizawa  1 , Hiroko Kanda, Kojiro Sato, Kimito Kawahata, Akihiro Yamaguchi, Hiroshi Uozaki, Jun Shimizu, Shoji Tsuji, Yoshikata Misaki, Kazuhiko Yamamoto
Affiliations
Case Reports

Polymyositis associated with focal mesangial proliferative glomerulonephritis with depositions of immune complexes

Yasunobu Takizawa et al. Clin Rheumatol. 2007 May.

Abstract

A 58-year-old man concurrently developed polymyositis (PM), interstitial lung disease, and nephrotic-range proteinuria. Renal biopsy revealed focal mesangial proliferative glomerulonephritis (mesPGN) with depositions of immunoglobulin and complements. A combination therapy of corticosteroid, intravenous immunoglobulin, and cyclosporine was found very effective for the patient. Glomerulonephritis associated with PM/dermatomyositis (DM) is rare. In our review of related literature, mesPGN was exclusively observed in polymyositis while membranous nephropathy in DM. The mechanism underlying the association between myositis and glomerulonephritis remains to be elucidated.

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References

    1. Ryumachi. 1981;21 Suppl:183-8 - PubMed
    1. Arch Intern Med. 1977 Jul;137(7):939-41 - PubMed
    1. N Engl J Med. 1991 Nov 21;325(21):1487-98 - PubMed
    1. Am J Nephrol. 2002 Jul-Aug;22(4):385-8 - PubMed
    1. Nihon Naika Gakkai Zasshi. 1989 Jul;78(7):994-5 - PubMed

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