Comment
doi: 10.1016/j.molcel.2006.03.004.
The double-edged sword of Nrf2: subversion of redox homeostasis during the evolution of cancer
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- PMID: 16543142
- DOI: 10.1016/j.molcel.2006.03.004
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Comment
The double-edged sword of Nrf2: subversion of redox homeostasis during the evolution of cancer
Mol Cell.
.
Free article
Abstract
Low levels of Nrf2 activity predispose cells to chemical carcinogenesis. Surprisingly, Padmanabhan et al. (2006) provide evidence in a recent issue of Molecular Cell to support the notion that elevated Nrf2 activity may also play a role in the evolution of cancer.
Comment on
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Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.Mol Cell. 2006 Mar 3;21(5):689-700. doi: 10.1016/j.molcel.2006.01.013. Mol Cell. 2006. PMID: 16507366
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