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Review
. 2006 Mar 18;332(7542):639-42.
doi: 10.1136/bmj.332.7542.639.

Osteoarthritis

David J Hunter  1 , David T Felson
Affiliations
Review

Osteoarthritis

David J Hunter et al. BMJ. .
No abstract available

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Figures

Fig 1
Fig 1
Pathogenic features consistent with osteoarthritis (“joint failure”)
Fig 2
Fig 2
Frontal x ray of knee showing advanced osteoarthritis. Note the narrowing of the joint space, gas within the joint space, sclerosis, and bony spur formation along the margins of the distal femur and proximal tibia
Fig 3
Fig 3
Stepwise algorithm for the management of patients with osteoarthritis. This is an example of a treatment algorithm that is modified according to patient's response and clinician's preference. It highlights the encompassing need to consider non-pharmacological management as first line for all patients
See this image and copyright information in PMC

Comment in

References

    1. Martin JA, Buckwalter JA. Roles of articular cartilage aging and chondrocyte senescence in the pathogenesis of osteoarthritis. Iowa Orthop J 2001;21: 1-7. - PMC - PubMed
    1. Nuki G. Osteoarthritis: a problem of joint failure. Z Rheumatol 1999;58: 142-7. - PubMed
    1. Peach CA, Carr AJ, Loughlin J. Recent advances in the genetic investigation of osteoarthritis. Trends Mol Med 2005;11: 186-91. - PubMed
    1. Peat G, McCarney R, Croft P. Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis 2001;60: 91-7. - PMC - PubMed
    1. Dieppe PA, Lohmander LS. Pathogenesis and management of pain in osteoarthritis. Lancet 2005;365: 965-73. - PubMed

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