Clinical insights into paraneoplastic cerebellar degeneration
- PMID: 16543537
- PMCID: PMC2077487
- DOI: 10.1136/jnnp.2005.082206
Clinical insights into paraneoplastic cerebellar degeneration
Abstract
Neuroimaging is usually unremarkable in paraneoplastic cerebellar degeneration (PCD), at least in the early stages of the disease. A patient with proven PCD is reported in whom it could be shown that cerebellar atrophy evolved very rapidly and was present in early imaging studies. Even with the use of the whole spectrum of modern diagnostic tools, the underlying malignancy can be difficult to diagnose. In addition to mammography, MRI is recommended in these cases and repeat FDG-PET may be necessary.
Conflict of interest statement
Competing interests: none declared
Comment in
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Paraneoplastic cerebellar degeneration: new insights into imaging and immunology.J Neurol Neurosurg Psychiatry. 2006 Apr;77(4):427. doi: 10.1136/jnnp.2005.082339. J Neurol Neurosurg Psychiatry. 2006. PMID: 16543516 Free PMC article.
References
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- Geomini P M, Dellemijn P L, Bremer G L. Paraneoplastic cerebellar degeneration: neurological symptoms pointing to occult ovarian cancer. Gynecol Obstet Invest 200152145–146. - PubMed
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