Review
doi: 10.1016/j.jclinepi.2005.12.001.
The nature and power of the placebo effect
Affiliations
- PMID: 16549251
- DOI: 10.1016/j.jclinepi.2005.12.001
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Review
The nature and power of the placebo effect
J Clin Epidemiol.
2006 Apr.
Abstract
Progress in understanding the placebo effect and its clinical significance depends on conceptual clarification of this elusive phenomenon and critical appraisal of research bearing on the influence of placebo interventions on clinical outcomes. Here we locate the placebo effect within a typology of modes of healing, distinguish between the observed placebo response in randomized controlled trials and the placebo effect, and examine critically a recent meta-analysis of clinical trials that challenges the reality of the placebo effect.
Comment in
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Unsubstantiated claims of large effects of placebo on pain: serious errors in meta-analysis of placebo analgesia mechanism studies.J Clin Epidemiol. 2006 Apr;59(4):336-8; discussion 339-41. doi: 10.1016/j.jclinepi.2005.05.011. J Clin Epidemiol. 2006. PMID: 16549252 No abstract available.
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