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. 1991 Aug;49(2):134-7.
doi: 10.1007/BF02565136.

Adsorption and mineralization effects of citrate and phosphocitrate on hydroxyapatite

M Johnsson  1 , C F Richardson, J D Sallis, G H Nancollas
Affiliations

Adsorption and mineralization effects of citrate and phosphocitrate on hydroxyapatite

M Johnsson et al. Calcif Tissue Int. 1991 Aug.

Abstract

The adsorption of citrate and phosphocitrate ions by hydroxyapatite (HAP) surfaces and their influence on the constant composition growth kinetics of HAP have been investigated. Phosphocitrate was strongly adsorbed to HAP and inhibited crystal growth. When HAP surfaces containing preadsorbed citrate were exposed to phosphocitrate, the uptake of the latter markedly increased. The two additives behaved synergistically in their HAP crystal growth inhibition.

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