Binding of drugs to hepatic microsomes: comment and assessment of current prediction methodology with recommendation for improvement
- PMID: 16552024
- DOI: 10.1124/dmd.105.007658
Binding of drugs to hepatic microsomes: comment and assessment of current prediction methodology with recommendation for improvement
Erratum in
- Drug Metab Dispos. 2006 Jun;34(6):1078
Comment on
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The binding of drugs to hepatocytes and its relationship to physicochemical properties.Drug Metab Dispos. 2005 Mar;33(3):419-25. doi: 10.1124/dmd.104.002436. Epub 2004 Dec 22. Drug Metab Dispos. 2005. PMID: 15616151
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A unified model for predicting human hepatic, metabolic clearance from in vitro intrinsic clearance data in hepatocytes and microsomes.Drug Metab Dispos. 2005 Sep;33(9):1304-11. doi: 10.1124/dmd.105.004259. Epub 2005 Jun 2. Drug Metab Dispos. 2005. PMID: 15932954
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