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Review
. 2006 Apr;3(2):170-80.
doi: 10.1016/j.nurx.2006.01.013.

New generation anticonvulsants for the treatment of epilepsy in children

Elizabeth J Donner  1 , O Carter Snead 3rd
Affiliations
Review

New generation anticonvulsants for the treatment of epilepsy in children

Elizabeth J Donner et al. NeuroRx. 2006 Apr.

Abstract

In the last 12 years, 10 new anticonvulsants have been approved by the U.S. Food and Drug Administration and, as a result, the treatment options for children and adults with epilepsy have been expanded considerably. These new generation antiepileptic drugs offer equal efficacy with improved tolerability, pharmacokinetic properties, and side effect profiles compared with the traditional drugs. With many new medications available, the clinician treating children with epilepsy must be well versed in the application of these drugs to their patient population. This manuscript will review the indications, mechanism of action, pharmacokinetics, adverse effects, and dosing of the new generation of anticonvulsant medications.

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