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. 2006 Mar;7(3):272-81.

Clazosentan (Actelion)

Affiliations
  • PMID: 16555688

Clazosentan (Actelion)

Dirk Uhlmann. Curr Opin Investig Drugs. 2006 Mar.

Abstract

Clazosentan, an endothelin ETA antagonist, is under development by Actelion (formerly Axovan), under license from F Hoffman-La Roche, for the potential prevention of cerebral infarction and ischemia induced by cerebral vasospasm following subarachnoid hemorrhage. Results from the phase IIb portion of a phase IIb/III clinical study are expected in the first half of 2006.

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