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. 2006 May;37(5):1332-3.
doi: 10.1161/01.STR.0000217272.38455.a2. Epub 2006 Mar 23.

Good outcomes in ischemic stroke patients treated with intravenous thrombolysis despite regressing neurological symptoms

Christian R Baumann  1 , Ralf W Baumgartner, Joubin Gandjour, Hans-Christian von Büdingen, Adrian M Siegel, Dimitrios Georgiadis
Affiliations

Good outcomes in ischemic stroke patients treated with intravenous thrombolysis despite regressing neurological symptoms

Christian R Baumann et al. Stroke. 2006 May.

Abstract

Background and purpose: We evaluated the clinical course of 19 acute stroke patients with rapid early improvement of neurological deficit within the 3-hour window, treated with intravenous thrombolytics.

Results: No patient demonstrated a neurological deterioration during hospitalization. National Institutes of Health Stroke Scale (NIHSS) scores at therapy decision and discharge were 5 (4 to 6) and 0.5 (0 to 1.5), respectively. At 3-month follow-up, 1 patient had died; in remaining patients, NIHSS was 0 (0 to 1) and modified Rankin Scale 0.5 (0 to 1; < or =1 in 15 patients).

Conclusions: Withholding of intravenous thrombolysis because of spontaneous early regression of neurological symptoms may not be justified.

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