Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 May;34(5):1333-7.
doi: 10.1097/01.CCM.0000214677.76535.A5.

Fluid challenge revisited

Affiliations
Review

Fluid challenge revisited

Jean-Louis Vincent et al. Crit Care Med. 2006 May.

Abstract

Objective: To discuss the rationale, technique, and clinical application of the fluid challenge.

Data source: Relevant literature from MEDLINE and authors' personal databases.

Study selection: Studies on fluid challenge in the acutely ill.

Data extraction: Based largely on clinical experience and assessment of the relevant published literature, we propose that the protocol should include four variables, namely 1) the type of fluid administered, 2) the rate of fluid administration, 3) the critical end points, and 4) the safety limits.

Conclusions: A protocol for routine fluid challenge is proposed with defined rules and based on the patient's response to the volumes infused. The technique allows for prompt correction of fluid deficits yet minimizes the risks of fluid overload.

Learning objectives: On completion of this article, the reader should be able to: 1. Explain the signs of hypovolemia. 2. Describe how to administer a fluid challenge. 3. Use this information in a clinical setting.

PubMed Disclaimer

Comment in

  • Monitoring of goal-directed fluid challenge.
    Harms MP, Secher NH, van Lieshout JJ. Harms MP, et al. Crit Care Med. 2007 Feb;35(2):673; author reply 673-4. doi: 10.1097/01.CCM.0000254332.29816.C6. Crit Care Med. 2007. PMID: 17251732 No abstract available.

LinkOut - more resources