Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1970 Mar;1(3):259-62.
doi: 10.1128/iai.1.3.259-262.1970.

Plaque formation by Chlamydia in L cells

J Banks  1 , B Eddie, J Schachter, K F Meyer
Affiliations

Plaque formation by Chlamydia in L cells

J Banks et al. Infect Immun. 1970 Mar.

Abstract

Chlamydiae were found capable of producing plaques in several cell lines. Mouse fibroblast cells, L-929, proved the most sensitive to infection and yielded plaques of the highest clarity. Assay of chlamydial infectivity by plaque titration was at least as sensitive as egg ld(50) determination. Among chlamydial isolates of avian, mammalian, and human origin, only slow-growing trachoma-inclusion-conjunctivitis agents did not produce plaques. The plaque assay is highly sensitive, reproducible, and offers a potential tool for investigations requiring accurate measurement of small changes in chlamydial infectivity.

PubMed Disclaimer

References

    1. J Bacteriol. 1964 Aug;88:533-4 - PubMed
    1. Am J Ophthalmol. 1967 May;63(5):Suppl:1206-11 - PubMed
    1. Proc Natl Acad Sci U S A. 1952 Aug;38(8):747-52 - PubMed
    1. Virology. 1960 Dec;12:578-88 - PubMed
    1. J Bacteriol. 1969 May;98(2):475-80 - PubMed