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. 2006 Mar 24;124(6):1111-5.
doi: 10.1016/j.cell.2006.03.011.

Stem cells and cancer: two faces of eve

Michael F Clarke  1 , Margaret Fuller
Affiliations
Free article

Stem cells and cancer: two faces of eve

Michael F Clarke et al. Cell. .
Free article

Abstract

Recent evidence suggests that a subset of cancer cells within some tumors, the so-called cancer stem cells, may drive the growth and metastasis of these tumors. Understanding the pathways that regulate proliferation, self-renewal, survival, and differentiation of malignant and normal stem cells may shed light on mechanisms that lead to cancer and suggest better modes of treatment.

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