Review
doi: 10.1016/j.cell.2006.03.008.
The KEOPS complex: a rosetta stone for telomere regulation?
Affiliations
- PMID: 16564005
- DOI: 10.1016/j.cell.2006.03.008
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Review
The KEOPS complex: a rosetta stone for telomere regulation?
Cell.
.
Free article
Abstract
The detailed mechanisms underlying telomere capping and its relationship to telomerase activity are still unclear, although many proteins have been implicated in either or both processes. In this issue of Cell, the surprising identification of a new complex, called KEOPS, which promotes both telomere uncapping and elongation is presented.
Comment on
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A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.Cell. 2006 Mar 24;124(6):1155-68. doi: 10.1016/j.cell.2005.12.044. Cell. 2006. PMID: 16564010
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