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Comparative Study
. 2006 Apr;134(4):592-5.
doi: 10.1016/j.otohns.2005.11.025.

Incidence of skull base and orbital erosion in allergic fungal rhinosinusitis (AFRS) and non-AFRS

Mark D Ghegan  1 , Fu-Shing Lee, Rodney J Schlosser
Affiliations
Comparative Study

Incidence of skull base and orbital erosion in allergic fungal rhinosinusitis (AFRS) and non-AFRS

Mark D Ghegan et al. Otolaryngol Head Neck Surg. 2006 Apr.

Abstract

Objective: To compare the incidence of bony erosion associated with allergic fungal rhinosinusitis (AFRS) with the incidence of bony erosion seen in other types of inflammatory sinusitis.

Study design: Retrospective review.

Results: AFRS was diagnosed in 27 patients, and 15/27 (56%) had bony skull base or orbital erosion. Non-AFRS chronic sinusitis required surgery in 158 patients, but only 8 (5%) had bony skull base or orbital erosion (P < 0.01). AFRS patients were 12.6 times (P < 0.01) more likely to have bony erosion than non-AFRS patients. African American males were 15.0 times (P < 0.01) more likely to have bony erosion than whites and African American females combined.

Conclusion: Bony erosion with intracranial and intraorbital extension is much more common in AFRS than all other types of inflammatory sinusitis combined. African American males have a higher incidence of AFRS, as well as intracranial and intraorbital extension.

Ebm rating: C-4.

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