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Review
. 2006 Apr:21:115-23.
doi: 10.1152/physiol.00052.2005.

The ins and outs of iron homeostasis

Adriana Donovan  1 , Cindy N Roy, Nancy C Andrews
Affiliations
Free article
Review

The ins and outs of iron homeostasis

Adriana Donovan et al. Physiology (Bethesda). 2006 Apr.
Free article

Abstract

Iron is an essential element that is toxic when it accumulates in excess. Intricate regulatory mechanisms have evolved to maintain iron homeostasis within cells and between different tissues of complex organisms. This review discusses the proteins involved in iron transport and storage and their regulation in health and disease.

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