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Review
. 2006 Apr:21:124-33.
doi: 10.1152/physiol.00043.2005.

Dense-core secretory granule biogenesis

Taeyoon Kim  1 , Marjorie C Gondré-Lewis, Irina Arnaoutova, Y Peng Loh
Affiliations
Free article
Review

Dense-core secretory granule biogenesis

Taeyoon Kim et al. Physiology (Bethesda). 2006 Apr.
Free article

Abstract

The dense-core secretory granule is a key organelle for secretion of hormones and neuropeptides in endocrine cells and neurons, in response to stimulation. Cholesterol and granins are critical for the assembly of these organelles at the trans-Golgi network, and their biogenesis is regulated quantitatively by posttranscriptional and posttranslational mechanisms.

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