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Controlled Clinical Trial
. 2006 May;85(5):1541-3.
doi: 10.1016/j.fertnstert.2005.10.052. Epub 2006 Mar 29.

Elevated serum müllerian-inhibiting substance may be a marker for ovarian hyperstimulation syndrome in normal women undergoing in vitro fertilization

Gary S Nakhuda  1 , Micheline C Chu, Jeff G Wang, Mark V Sauer, Rogerio A Lobo
Affiliations
Free article
Controlled Clinical Trial

Elevated serum müllerian-inhibiting substance may be a marker for ovarian hyperstimulation syndrome in normal women undergoing in vitro fertilization

Gary S Nakhuda et al. Fertil Steril. 2006 May.
Free article

Abstract

We identified patients who experienced ovarian hyperstimulation syndrome (OHSS) (n = 16) and compared their baseline pretreatment levels of müllerian-inhibiting substance (MIS) to age- and weight-matched patients with normal responses to gonadotropins (n = 14). Baseline serum MIS in patients with OHSS were sixfold higher than those seen in normal controls (3.62 +/- 0.87 vs. 0.63 +/- 0.09 ng/mL; P=.0036), indicating that MIS could potentially serve as a useful marker for identifying patients at risk for OHSS.

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