Review
doi: 10.1007/3-540-26397-7_9.
Hepatitis C virus population dynamics during infection
Affiliations
- PMID: 16568902
- DOI: 10.1007/3-540-26397-7_9
Item in Clipboard
Review
Hepatitis C virus population dynamics during infection
Curr Top Microbiol Immunol.
2006.
Abstract
Hepatitis C virus (HCV) behaves as an evolving viral quasispecies in its continuously changing environment. The study of HCV quasispecies population dynamics in experimental models and infected patients can provide useful information on factors involved in the HCV life cycle and pathogenicity. HCV quasispecies variability also has therapeutic implications, as the continuous generation and selection of fitter or truly resistant variants can allow the virus to escape control by antiviral drugs.
Similar articles
-
Hepatitis C virus genetic variability: pathogenic and clinical implications.Clin Liver Dis. 2003 Feb;7(1):45-66. doi: 10.1016/s1089-3261(02)00065-x. Clin Liver Dis. 2003. PMID: 12691458 Review.
-
Inter and intrapatient evolution of hepatitis C virus.Ann Hepatol. 2015 Jul-Aug;14(4):442-9. Ann Hepatol. 2015. PMID: 26019029 Review.
-
The history of hepatitis C virus (HCV): Basic research reveals unique features in phylogeny, evolution and the viral life cycle with new perspectives for epidemic control.J Hepatol. 2016 Oct;65(1 Suppl):S2-S21. doi: 10.1016/j.jhep.2016.07.035. J Hepatol. 2016. PMID: 27641985 Review.
-
Experimental infection of chimpanzees with hepatitis C virus of genotype 5a: genetic analysis of the virus and generation of a standardized challenge pool.J Infect Dis. 1998 Oct;178(4):1193-7. doi: 10.1086/515683. J Infect Dis. 1998. PMID: 9806059
-
Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification.J Virol. 2015 Oct 14;90(1):152-66. doi: 10.1128/JVI.02156-15. Print 2016 Jan 1. J Virol. 2015. PMID: 26468546 Free PMC article.
Cited by
-
Resistance Mechanisms in Hepatitis C Virus: implications for Direct-Acting Antiviral Use.Drugs. 2017 Jul;77(10):1043-1055. doi: 10.1007/s40265-017-0753-x. Drugs. 2017. PMID: 28497432 Review.
-
Analysis of hepatitis C virus intrahost diversity across the coding region by ultradeep pyrosequencing.J Virol. 2012 Apr;86(7):3952-60. doi: 10.1128/JVI.06627-11. Epub 2012 Jan 25. J Virol. 2012. PMID: 22278255 Free PMC article.
-
Era of direct acting anti-viral agents for the treatment of hepatitis C.World J Hepatol. 2018 Oct 27;10(10):670-684. doi: 10.4254/wjh.v10.i10.670. World J Hepatol. 2018. PMID: 30386460 Free PMC article. Review.
-
Biomarkers in Detection of Hepatitis C Virus Infection.Pathogens. 2024 Apr 17;13(4):331. doi: 10.3390/pathogens13040331. Pathogens. 2024. PMID: 38668286 Free PMC article. Review.
-
Sequencing of the Hepatitis C Virus: A Systematic Review.PLoS One. 2013 Jun 27;8(6):e67073. doi: 10.1371/journal.pone.0067073. Print 2013. PLoS One. 2013. PMID: 23826196 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
