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. 2006 Apr;50(4):1570-2.
doi: 10.1128/AAC.50.4.1570-1572.2006.

Voriconazole therapeutic drug monitoring

J Smith  1 , N Safdar, V Knasinski, W Simmons, S M Bhavnani, P G Ambrose, D Andes
Affiliations

Voriconazole therapeutic drug monitoring

J Smith et al. Antimicrob Agents Chemother. 2006 Apr.

Abstract

We report on 28 patients who underwent voriconazole monitoring because of disease progression or toxicity. A relationship (P<0.025) between disease progression and drug concentration was detected. Favorable responses were observed in 10/10 patients with concentrations above 2.05 microg/ml, while disease progressed in 44% (n=18) of patients with concentrations below 2.05 microg/ml.

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