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. 1991;241(2):85-7.
doi: 10.1007/BF02191146.

Platelet imipramine binding in intensive care unit suicidal patients

D De Leo  1 , A Caneva, D Marazziti, L Conti
Affiliations

Platelet imipramine binding in intensive care unit suicidal patients

D De Leo et al. Eur Arch Psychiatry Clin Neurosci. 1991.

Abstract

3H-Imipramine binding in relation to serotonergic function was studied in patients hospitalized following a suicide attempt. Comparison with a control group showed a highly significant difference in Bmax values. The results suggest, at least a posteriori, a biological alteration as the basis of suicidal behaviour. Although it is impossible to attribute a suicidal attempt to the alteration or to a predisposing pre-existent condition, this biological marker may be useful in evaluating suicidal risk and also short- and long-term prognosis.

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