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Review
. 2006 Mar-Apr;25(2):140-5; quiz 146-7.
doi: 10.1097/00006416-200603000-00013.

The pathogenesis of systemic lupus erythematosus

Review

The pathogenesis of systemic lupus erythematosus

Sharon G Childs. Orthop Nurs. 2006 Mar-Apr.

Abstract

Systemic lupus erythematosus is an autoimmune disease that causes inflammation in the tissues of the brain, endothelial cells, gastrointestinal/genitourinary (GI/GU), joints, kidneys, muscles, and skin. Lupus comprises a range of multisystem disorders involving the deposition of aberrant immune complexes into tissues. Inflammation occurs as a result of autoantibodies attacking organ systems. The pathogenesis of systemic lupus erythematosus is presented.

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