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Review
. 2006 Apr;23(2):256-320.
doi: 10.1039/b301028g. Epub 2005 Dec 19.

The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites

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Review

The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites

Alison M Hill. Nat Prod Rep. 2006 Apr.

Abstract

This review covers the biosynthesis of aliphatic and aromatic polyketides as well as mixed polyketide/NRPS metabolites, and discusses the molecular genetics and enzymology of the proteins responsible for their formation.

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