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. 2006 Feb;31(2):131-5.
doi: 10.1007/s11064-005-9014-6. Epub 2006 Mar 30.

From punch to profile

E Ronald de Kloet  1
Affiliations

From punch to profile

E Ronald de Kloet. Neurochem Res. 2006 Feb.

Abstract

In this essay an aspect of my research is highlighted that has its roots in the mid seventies with the implementation of the 'Palkovits punch' procedure. This methodology was introduced when radiochemical and radio-immunoassay methods became sufficiently sensitive to measure key molecules for chemical neurotransmission and metabolism in minute amounts of brain tissue. For application of today's laser guided microdissection this knowledge of functional neuro-anatomy is indispensable.

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