Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Mar 30:4:19.
doi: 10.1186/1477-7819-4-19.

Perforated gastric carcinoma: a report of 10 cases and review of the literature

Franco Roviello  1 , Simone Rossi, Daniele Marrelli, Giovanni De Manzoni, Corrado Pedrazzani, Paolo Morgagni, Giovanni Corso, Enrico Pinto
Affiliations

Perforated gastric carcinoma: a report of 10 cases and review of the literature

Franco Roviello et al. World J Surg Oncol. .

Abstract

Background: Perforation is a rare complication of gastric carcinoma, accounting for less than 1% of all gastric cancer cases. The aim of the present study is to evaluate the prognostic value of perforation and to point out the surgical treatment options.

Methods: A total of 10 patients with perforated gastric carcinoma were retrospectively reviewed among 2564 consecutive cases of gastric cancer operated in three Centers belonging to the Italian Research Group for Gastric Cancer. The clinicopathological features including tumor stage and survival were analyzed and compared to literature data.

Results: Incidence rate was 0.39%. All patients underwent emergency surgery, being performed gastrectomy in 6 patients (mortality 17%) and repair surgery in 4 patients (mortality 75%). The survival of patients was related to the stage of the disease, with 2 long-survival cases.

Conclusion: Perforation usually occurs in advanced stages of gastric cancer; nevertheless surgeons should not be always discouraged from a radical treatment of perforated gastric cancer, since perforation even occurs in early stages and seems not to be a negative prognostic factor itself. When possible, emergency gastrectomy should be performed, leaving repair surgery for unresectable tumors. A two-stage treatment is a good treatment option for frail patients with resectable tumors.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Decisional flow-chart for perforated gastric cancer. General condition includes 3 factors: haemodynamics, gravity of peritonitis and comorbidities.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Adachi Y, Mori M, Maehara Y, Matsumata T, Okudaira Y, Sugimachi K. Surgical results of perforated gastric carcinoma: an analysis of 155 Japanese patients. Am J Gastroenterol. 1997;92:516–8. - PubMed
    1. Kasakura Y, Ajani JA, Fujii M, Mochizuki F, Takayama T. Management of perforated gastric carcinoma: a report of 16 cases and review of world literature. Am Surg. 2002;68:434–40. - PubMed
    1. Stechenberg L, Bunch RH, Anderson MC. The surgical therapy for perforated gastric cancer. Am Surg. 1981;47:208–210. - PubMed
    1. McNealy RW, Hedin RF. Perforation in gastric carcinoma. J Am Coll Surg. 1938;67:818–823.
    1. Bisgard JD. Gastric resection for certain acute perforated lesions of stomach and duodenum with diffuse soiling of the peritoneal cavity. Surgery. 1945;17:498–509.