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. 2006 Apr;17(2):230-2.
doi: 10.1016/j.semcdb.2006.02.001. Epub 2006 Feb 23.

ITP

Affiliations

ITP

Michael Whitaker. Semin Cell Dev Biol. 2006 Apr.

Abstract

I describe how we came to microinject inositol trisphosphate into sea urchin eggs and found that is was a very potent activator of calcium release.

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Figures

Figure 1
Figure 1
Problems with the controls. A page from the lab book.
Figure 2
Figure 2
Learning the nomenclature. Entries in the lab book use ITP as an abbrieviation for inositol 1,4,5-trisphosphate. (a) Summary of experimental data in a spreadsheet-free era; (b) An early draft of a figure (top left) uses ITP, not Ins 1 4 5 P3; the later draft of the figure and some photographs of InsP3-activated eggs are also shown.
Figure 2
Figure 2
Learning the nomenclature. Entries in the lab book use ITP as an abbrieviation for inositol 1,4,5-trisphosphate. (a) Summary of experimental data in a spreadsheet-free era; (b) An early draft of a figure (top left) uses ITP, not Ins 1 4 5 P3; the later draft of the figure and some photographs of InsP3-activated eggs are also shown.

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References

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    1. Baker PF, Whitaker MJ. Influence of ATP and calcium on the cortical reaction in sea urchin eggs. Nature. 1978;276:513–515. - PubMed

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