Xenotransplantation: a bioethical evaluation
- PMID: 16574873
- PMCID: PMC2565783
- DOI: 10.1136/jme.2005.012914
Xenotransplantation: a bioethical evaluation
Abstract
Allograft shortage is a formidable obstacle in organ transplantation. Xenotransplantation, the interspecies transplantation of cells, tissues, and organs, or ex vivo interspecies exchange between cells, tissues, and organs is a frequently suggested alternative to this allograft shortage. As xenotransplantation steadily improves into a viable allotransplantation alternative, several bioethical considerations coalesce. Such considerations include the Helsinki declaration's guarantee of patients' rights to privacy; political red tape that may select for undermined socioeconomic groups as the first recipients of xenografts; industry incentives in xenotransplantation investments; conflicts of interest when a clinician supervises a patient as a research subject; the psychosocial impact of transplantation on the xenograft recipient, and the rights of animals. This review illuminates these issues through a conglomeration of expert opinion and relevant experimental studies.
References
-
- Institute of Medicine (IOM) Xenotransplantation: science, ethics, and public policy. Washington, DC: National Academy Press, 1996 - PubMed
-
- Sykes M, d'Apase A, Sandrin M. Position paper of the Ethics Committee of the International Xenotransplantation Association. Xenotransplantation 200310194–203. - PubMed
-
- Daar A S, Phil D. Ethics of xenotransplantation: animal issues, consent, and likely transformation of transplantation ethics. World J Surg 199721975–982. - PubMed
-
- Melo H, Brandao C, Rego G.et al Ethical and legal issues in xenotransplanation, Bioethics2001151–16. - PubMed
-
- Reemtsma K. Xenotransplantation—a brief history of clinical experiences: 1900–1965. In: Cooper DKC, Reemtsma K, White D, eds. Xenotransplantation. The transplantation of organs and tissues between species. Berlin: Springer‐Verlag, 199110–12.
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