Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Dec;59(12):4706-9.
doi: 10.1128/iai.59.12.4706-4709.1991.

Experimental Porphyromonas gingivalis infection in nonimmune athymic BALB/c mice

P B Chen  1 , L B Davern, A Aguirre
Affiliations

Experimental Porphyromonas gingivalis infection in nonimmune athymic BALB/c mice

P B Chen et al. Infect Immun. 1991 Dec.

Abstract

The purpose of this report was to study the role of T lymphocytes following injection of Porphyromonas gingivalis in a mouse abscess model. Three invasive P. gingivalis isolates (ATCC 53977, W83, and AJW4) were injected into athymic BALB/c mice and their heterozygous (nu/+) littermates. The athymic BALB/c (nu/nu) mice were able to localize the invasive P. gingivalis isolates at the injection site. By comparison, the heterozygous BALB/c (nu/+) littermates developed hemorrhagic secondary lesions within 24 h after subcutaneous injection of the same invasive P. gingivalis isolates. These results suggest that naive T lymphocytes may contribute to the pathology associated with P. gingivalis infection.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. J Med Microbiol. 1988 Oct;27(2):109-16 - PubMed
    1. J Immunol. 1975 Sep;115(3):844-7 - PubMed
    1. J Clin Periodontol. 1988 May;15(5):316-23 - PubMed
    1. J Clin Periodontol. 1988 Mar;15(3):145-55 - PubMed
    1. Annu Rev Immunol. 1987;5:367-403 - PubMed

Publication types

LinkOut - more resources