doi: 10.1073/pnas.86.12.4559.
cricklet: A locus regulating a number of adult functions of Drosophila melanogaster
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- PMID: 16578845
- PMCID: PMC287310
- DOI: 10.1073/pnas.86.12.4559
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cricklet: A locus regulating a number of adult functions of Drosophila melanogaster
Proc Natl Acad Sci U S A.
1989 Jun.
Abstract
During a screen for mutations in trans-acting genes regulating yolk protein synthesis in Drosophila melanogaster, we have isolated a mutant (cricklet, clt) that is defective in yolk protein synthesis, histolysis of the larval fat body, vitellogenesis, and synthesis of larval serum protein 2 in the adult, larval synthesis occurring normally. Larval serum protein 2 was previously thought to be synthesized only in the third-instar larva. We suggest that the clt locus may encode a protein essential for mediating the response of adult tissues to juvenile hormone.
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