Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Apr;10(4):415-7.
doi: 10.1016/j.devcel.2006.03.002.

Regulating quiescence: new insights into hematopoietic stem cell biology

Emmanuelle Passegué  1 , Amy J Wagers
Affiliations
Free article

Regulating quiescence: new insights into hematopoietic stem cell biology

Emmanuelle Passegué et al. Dev Cell. 2006 Apr.
Free article

Abstract

Blood-forming hematopoietic stem cells (HSCs) ensure production of all mature blood cells during homeostatic and regenerative hematopoiesis. Proliferation, cell cycle regulation, and quiescence are key processes involved in this function, and in a recent issue of Cancer Cell, show that HSC quiescence is actively regulated by specific molecular mechanisms that appear to distinguish normal HSC maintenance from HSC responses to hematologic injury.

PubMed Disclaimer

MeSH terms

LinkOut - more resources