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. 1978 Aug;75(8):3557-61.
doi: 10.1073/pnas.75.8.3557.

Decomposition of the linking number of a closed ribbon: A problem from molecular biology

F B Fuller  1
Affiliations

Decomposition of the linking number of a closed ribbon: A problem from molecular biology

F B Fuller. Proc Natl Acad Sci U S A. 1978 Aug.

Abstract

A closed duplex DNA molecule relaxed and containing nucleosomes has a different linking number from the same molecule relaxed and without nucleosomes. What does this say about the structure of the nucleosome? A mathematical study of this question is made, representing the DNA molecule by a ribbon. It is shown that the linking number of a closed ribbon can be decomposed into the linking number of a reference ribbon plus a sum of locally determined "linking differences."

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References

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    1. Nature. 1975 Dec 4;258(5534):398-402 - PubMed
    1. Proc Natl Acad Sci U S A. 1971 Apr;68(4):815-9 - PubMed

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