alpha-Amanitin resistance is developmentally regulated in carrot
- PMID: 16593558
- PMCID: PMC397653
- DOI: 10.1073/pnas.82.9.2799
alpha-Amanitin resistance is developmentally regulated in carrot
Abstract
Carrot cells are capable of inactivating alpha-amanitin only in embryogenic conditions (regenerating cells and embryoids). Instead, the mutant line a3 is capable of inactivating the drug also in nonembryogenic conditions (vegetative growth). The mutation is dominant in somatic hybrids and is pleiotropic, allowing expression during vegetative growth of other embryonal functions. The inactivation of alpha-amanitin is due to the oxidative activity of tyrosinase.
Similar articles
-
Temperature-sensitive RNA polymerase II mutations in Chinese hamster ovary cells.Proc Natl Acad Sci U S A. 1978 Jan;75(1):405-9. doi: 10.1073/pnas.75.1.405. Proc Natl Acad Sci U S A. 1978. PMID: 272657 Free PMC article.
-
α-amanitin resistance in Drosophila melanogaster: A genome-wide association approach.PLoS One. 2017 Feb 27;12(2):e0173162. doi: 10.1371/journal.pone.0173162. eCollection 2017. PLoS One. 2017. PMID: 28241077 Free PMC article.
-
Study on genes with altered expression in alpha-amanitin poisoned mice and evaluation on antagonistic effects of traditional Chinese medicines against toxicity of alpha-amanitin.Acta Biol Hung. 2009 Sep;60(3):281-91. doi: 10.1556/ABiol.60.2009.3.5. Acta Biol Hung. 2009. PMID: 19700387
-
A new method for the purification of the different stages of carrot embryoids.Plant Cell Rep. 1983 Aug;2(4):216-8. doi: 10.1007/BF00270108. Plant Cell Rep. 1983. PMID: 24258056
-
Possible involvement of DNA methylation on expression regulation of carrot LEC1 gene in its 5'-upstream region.Gene. 2009 May 15;437(1-2):22-31. doi: 10.1016/j.gene.2009.02.011. Epub 2009 Mar 3. Gene. 2009. PMID: 19264116
Cited by
-
Purification and Some Properties of a Daucus carota Lectin which Enhances the Activation of Prophenoloxidase by CaCl(2).Plant Physiol. 1990 Jun;93(2):657-61. doi: 10.1104/pp.93.2.657. Plant Physiol. 1990. PMID: 16667519 Free PMC article.
-
Modulation of auxin-binding proteins in cell suspensions : I. Differential responses of carrot embryo cultures.Plant Physiol. 1991 Sep;97(1):60-4. doi: 10.1104/pp.97.1.60. Plant Physiol. 1991. PMID: 16668416 Free PMC article.
-
Purification of a trypsin inhibitor secreted by embryogenic carrot cells.Plant Physiol. 1987 May;84(1):197-200. doi: 10.1104/pp.84.1.197. Plant Physiol. 1987. PMID: 16665398 Free PMC article.
-
Effect of 2,4-dichlorophenoxyacetic Acid on the expression of embryogenic program in carrot.Plant Physiol. 1986 Aug;81(4):1143-6. doi: 10.1104/pp.81.4.1143. Plant Physiol. 1986. PMID: 16664958 Free PMC article.
-
DNA methylation of embryogenic carrot cell cultures and its variations as caused by mutation, differentiation, hormones and hypomethylating drugs.Theor Appl Genet. 1989 Mar;77(3):325-31. doi: 10.1007/BF00305823. Theor Appl Genet. 1989. PMID: 24232608
References
LinkOut - more resources
Full Text Sources