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Review
. 2006 May;69(10):1722-5.
doi: 10.1038/sj.ki.5000391.

Unearthing uric acid: an ancient factor with recently found significance in renal and cardiovascular disease

T Nakagawa  1 , D-H Kang, D Feig, L G Sanchez-Lozada, T R Srinivas, Y Sautin, A A Ejaz, M Segal, R J Johnson
Affiliations
Free article
Review

Unearthing uric acid: an ancient factor with recently found significance in renal and cardiovascular disease

T Nakagawa et al. Kidney Int. 2006 May.
Free article

Abstract

Uric acid is strongly associated with cardiovascular and renal disease, but is usually not considered to have a causal role. However, recent experimental, epidemiological, and clinical studies provocatively suggest that uric acid may contribute to the development of hypertension, metabolic syndrome, and kidney disease in some patients. Clinical studies are urgently needed to examine this important possibility.

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