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Case Reports
. 2007 Jun;62(6):554-6.
doi: 10.1136/thx.2005.048652. Epub 2006 Apr 6.

Pseudomembranous colitis in four patients with cystic fibrosis following lung transplantation

B Yates  1 , D M Murphy, A J Fisher, F K Gould, J L Lordan, J H Dark, P A Corris
Affiliations
Case Reports

Pseudomembranous colitis in four patients with cystic fibrosis following lung transplantation

B Yates et al. Thorax. 2007 Jun.

Abstract

Pseudomembranous colitis is an uncommon complication in patients with cystic fibrosis, despite the use of multiple high-dose antibiotic regimens and the frequency of hospital admissions. Four patients from a total of 137 patients with cystic fibrosis undergoing lung transplantation are described who developed fulminant pseudomembranous colitis. Initial presentation was variable and the mortality rate was 50% despite urgent colectomy. In one case the presenting abdominal distension was thought to be due to meconium ileus equivalent. It is concluded that Clostridium difficile colitis may be a difficult diagnosis in patients with cystic fibrosis and follows a fulminant course after lung transplantation.

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Conflict of interest statement

Conflicts of interest: None.

References

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