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. 2005 Dec;149(2):265-6.
doi: 10.5507/bp.2005.037.

Applications of new laboratory marker assays in neurological diagnoses - a pilot study

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Applications of new laboratory marker assays in neurological diagnoses - a pilot study

David Stejskal et al. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005 Dec.

Abstract

225 consecutive patients with different neurological diseases and 101 individuals as the control were examined between 2002-2004. Cystatin C, arginase-I, tau-protein and beta-amyloid were measured. Individuals with CNS inflammation had significantly lower Cystatin-C index (CSF/serum) values. There was no diagnostic significance of the Arginase-I assay in CSF was verified. The CSF tau-protein/beta-amyloid index was shown to be a sufficient efficacy for neurodegenerative disease diagnosis.

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