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Case Reports
. 2006 Sep;165(9):648-51.
doi: 10.1007/s00431-006-0125-0. Epub 2006 Apr 7.

Medullary sponge kidney associated with distal renal tubular acidosis in a 5-year-old girl

Belde Kasap  1 , Alper Soylu, Oğuz Oren, Mehmet Türkmen, Salih Kavukçu
Affiliations
Case Reports

Medullary sponge kidney associated with distal renal tubular acidosis in a 5-year-old girl

Belde Kasap et al. Eur J Pediatr. 2006 Sep.

Abstract

Introduction: Medullary sponge kidney (MSK) is characterized by cystic dilatation of the inner medullary collecting ducts, which causes the kidneys to resemble a sponge.

Case report: Although distal renal tubular acidosis (dRTA) is commonly observed in patients with MSK, we report a 5-year-old girl with MSK who had features of both dRTA (nephrocalcinosis, hypercalciuria, hypocitraturia) and proximal tubular dysfunction (hyperuricosuria, impaired tubular phosphate reabsorption and proteinuria).

Discussion: Metabolic acidosis, hypercalciuria, hypocitraturia, tubular phosphate reabsorption and growth retardation in the patient improved with alkali therapy.

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