Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Jul;65(7):961-4.
doi: 10.1136/ard.2006.052688. Epub 2006 Apr 10.

Familial Mediterranean fever (FMF) and beyond: a new horizon. Fourth International Congress on the Systemic Autoinflammatory Diseases held in Bethesda, USA, 6-10 November 2005

S Ozen  1 , H M Hoffman, J Frenkel, D Kastner
Affiliations

Familial Mediterranean fever (FMF) and beyond: a new horizon. Fourth International Congress on the Systemic Autoinflammatory Diseases held in Bethesda, USA, 6-10 November 2005

S Ozen et al. Ann Rheum Dis. 2006 Jul.

Abstract

Autoinflammatory diseases are characterised by seemingly unprovoked inflammation. They can be categorised as: hereditary (monogenic) autoinflammatory diseases, complex (polygenic/multifactorial) autoinflammatory diseases, and diseases where the course is affected by mutations in the defined autoinflammatory disease genes. Identification of the inflammatory pathways involved has opened up new areas of research which have implications for the treatment of these disorders and the pathogenesis of common inflammatory diseases.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Stojanov S, Kastner D L. Familal autoinflammatory diseases: genetics, pathogenesis and treatment. Curr Opin Rheumatol 200517586–599. - PubMed
    1. Livneh A, Langevitz P, Zemer D, Padeh S, Migdal A, Sohar E.et al The changing face of familial Mediterranean fever. Semin Arthritis Rheum 199626612–627. - PubMed
    1. Ozen S. Renal amyloidosis in familial Mediterranean fever. Kidney Int 2004651118–1127. - PubMed
    1. Samuels J, Ozen S. FMF and the other autoinflammatory syndromes: evaluation of the patient with recurrent fever. Curr Opin Rheumatol 200618108–117. - PubMed
    1. Chae J J, Komarow H D, Cheng J, Wood G, Raben N, Liu P P.et al Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol Cell 200311591–604. - PubMed

Publication types

MeSH terms