Direct catalytic asymmetric anti-selective Mannich-type reactions
- PMID: 16609796
- DOI: 10.1039/b602221a
Direct catalytic asymmetric anti-selective Mannich-type reactions
Abstract
The simple chiral pyrrolidine catalyzed asymmetric anti-selective Mannich-type reaction is presented; the reaction gives the corresponding amino acid derivatives with 10:1- >19:1 dr and 97-99% ee.
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