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. 2006 Apr 28:(16):1760-2.
doi: 10.1039/b602221a. Epub 2006 Mar 15.

Direct catalytic asymmetric anti-selective Mannich-type reactions

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Direct catalytic asymmetric anti-selective Mannich-type reactions

Ismail Ibrahem et al. Chem Commun (Camb). .

Abstract

The simple chiral pyrrolidine catalyzed asymmetric anti-selective Mannich-type reaction is presented; the reaction gives the corresponding amino acid derivatives with 10:1- >19:1 dr and 97-99% ee.

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