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Review
. 2006 Mar 28;12(12):1966-8.
doi: 10.3748/wjg.v12.i12.1966.

Large Brunner's gland adenoma: case report and literature review

Alba Rocco  1 , Pasquale Borriello, Debora Compare, Patrizia De Colibus, Loredana Pica, Alessandro Iacono, Gerardo Nardone
Affiliations
Review

Large Brunner's gland adenoma: case report and literature review

Alba Rocco et al. World J Gastroenterol. .

Abstract

Brunner's gland adenoma (BGA) is a very rare benign tumour of the duodenum, which is usually asymptomatic and discovered incidentally at endoscopy. Occasionally, this lesion may be large, causing upper gastrointestinal haemorrhage or intestinal obstruction. The case had a large Brunner's gland adenoma, presenting melena that was managed by endoscopic excision.

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Figures

Figure 1
Figure 1
Evidence of polypoid mass in duodenal bulb extending to second duodenal portion (arrow).
Figure 2
Figure 2
Gland hyperproliferation extending beyond muscolaris mucosae reaching lower portion of duodenal villi with irregular and squat profile of these structures (A) (H&E, original magnification X4) and detail of interface between Brunner’s gland proliferation and duodenal mucosa with absence of muscularis mucosae and irregular profile of villi (B) (E&E, original magnification X20).
See this image and copyright information in PMC

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